Linear 1 3-diarylpropanoids
Medchemexpress LLC AKT-IN-6 | 1430056-54-4 | 99.1% | 389.43 | 1 ML
AKT-IN-6 is a potent Akt inhibitor that targets Akt1, Akt2, and Akt3 with IC50s below 500 nM. Akt is a central node in cell signaling, and its aberrant activation is linked to various complex diseases, including type-2 diabetes and cancer.
- Potent Akt inhibitor
- Targets Akt1, Akt2, and Akt3
- Suitable for research applications
Selleck Chemical LLC Chalcone
Chalcone (benzylideneacetophenone phenyl styryl ketone benzalacetophenone -phenylacrylophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds which are known collectively as chalcones with antibacterial antifungal antitumor and anti-inflammatory properties
Medchemexpress LLC Trans-chalcone | 614-47-1 | 98.8% | 208.26 g·mol⁻¹ | C15H12O | 50g
trans-Chalcone isolated from Aronia melanocarpa skin is a biphenolic core structure of flavonoids precursor trans-Chalcone is a potent fatty acid synthase (FAS) and -amylase inhibitor trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7 trans-Chalcone has antifungal and anticancer activity[1][2][3]
Medchemexpress LLC 4'-Hydroxychalcone | 2657-25-2 | 1 ML
4'-Hydroxychalcone is a chalcone isolated from licorice root with hepatoprotective activity. It inhibits TNFa-induced NF-κB activation via proteasome inhibition. It also induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria.
- Isolated from licorice root
- Exhibits hepatoprotective activity
- Inhibits TNFa-induced NF-κB activation through proteasome inhibition
- Induces rapid potassium release from mitochondrial vesicles
- Causes deterioration of respiratory control and oxidative phosphorylation
- Affects cancer cell viability
Medchemexpress LLC Chalcone | 94-41-7 | 100.0% | 50 MG
Chalcone is the parent α,β-unsaturated ketone scaffold used widely as a small-molecule research chemical and synthetic building block. Provided as a high-purity solid, it is used in medicinal chemistry, biochemical assays, and the synthesis of chalcone derivatives. Typical identifiers: CAS 94-41-7; formula C15H12O; molecular weight 208.25 g/mol.
- High purity suitable for research use.
- Useful building block for synthesis of bioactive derivatives.
- Compatible with DMSO; available as solution for screening.
- Supplied with certificate of analysis and safety data for quality and safety.
- Available in small-scale quantities for discovery research.
Medchemexpress LLC (±)-Naringenin | 67604-48-2 | 99.8% | 272.26 | 50 G
(±)-Naringenin is an orally available anti-inflammatory agent that can regulate both acute and chronic inflammation responses, while also showing antioxidant, neuroprotective, liver-protective, and anti-cancer effects. It promotes vasodilation in endothelial cells by activating BKCa channels in muscle cells and exerts protective effects against experimental colitis by inhibiting Toll-like receptor 4/NF-κB signaling, making it useful in studies related to sepsis, fulminant hepatitis, fibrosis, and cancer research.
- Regulates acute and chronic inflammation responses
- Exhibits antioxidant effects
- Provides neuroprotective benefits
- Offers liver-protective properties
- Shows anti-cancer effects
- Promotes vasodilation in endothelial cells
- Inhibits Toll-like receptor 4/NF-κB signaling
